http://www.nutritionandmetabolism.com/content/5/1/9

Considers:
1. Carbohydrate restriction improves glycemic control, the primary target of nutritional therapy and reduces insulin fluctuations.

2. Carbohydrate-restricted diets are at least as effective for weight loss as low-fat diets.

3. Substitution of fat for carbohydrate is generally beneficial for markers for and incidence of CVD.

4. Carbohydrate restriction improves the features of metabolic syndrome.

5. Beneficial effects of carbohydrate restriction do not require weight loss.

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http://www.nutritionandmetabolism.com/content/6/1/21

Low carb diet helps severe type 2 diabetics
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http://www.nutritionandmetabolism.com/content/3/1/22

Advice on a 20 % carbohydrate diet with some caloric restriction to obese patients with type 2 diabetes has lasting effect on bodyweight and glycemic control

and long-term success also shown in:
http://www.nutritionandmetabolism.com/content/5/1/14
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http://www.nutritionandmetabolism.com/content/2/1/31

carb restriction improves glycemic control
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http://www.nutritionandmetabolism.com/content/2/1/34

ketogenic to treat type 2 dm
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http://www.nutritionandmetabolism.com/content/6/1/10

case study, reduces schizophrenia symptoms
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http://www.nutritionandmetabolism.com/content/5/1/36

low carb vs. low glycemic diets
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http://www.nutritionandmetabolism.com/content/5/1/10

Has carbohydrate-restriction been forgotten as a treatment for diabetes mellitus? A perspective on the ACCORD study design

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http://www.nutritionandmetabolism.com/content/5/1/6

wow. men on low carb diet showed higher HDL if they ate eggs.
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http://www.nutritionandmetabolism.com/content/5/1/4

fat loss due to low carb diets vs. low fat diets use different molecular/genetic pathways
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http://www.nutritionandmetabolism.com/content/4/1/23

on low carb diets, no significant difference in lipid profiles if meat intake primarily red meat (saturated fat) vs. fish
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http://www.nutritionandmetabolism.com/content/4/1/5

not relevant, but interesting. low calorie ketogenic diet to treat brain cancer.
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http://www.nutritionandmetabolism.com/content/3/1/39

A Paleolithic diet confers higher insulin sensitivity, lower C-reactive protein and lower blood pressure than a cereal-based diet in domestic pigs

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http://www.nutritionandmetabolism.com/content/3/1/33

Equivalent glycemic load (EGL): a method for quantifying the glycemic responses elicited by low carbohydrate foods

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http://www.nutritionandmetabolism.com/content/3/1/24

even in the absence of weight loss, low carb diets improve lipid profiles and decrease cardiac risk (ie. decrease atherosclerosis risk)
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http://www.nutritionandmetabolism.com/content/3/1/20

there are multi-gene effects in response to a low carb diet, and people respond differently to the low carb diet based on genetic makeup
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http://www.nutritionandmetabolism.com/content/3/1/19

Effects of a carbohydrate-restricted diet on emerging plasma markers for cardiovascular disease

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http://www.nutritionandmetabolism.com/content/3/1/9

a low carb diet that also has adequate levels of protein will preserve muscle mass during weight loss
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http://www.nutritionandmetabolism.com/content/3/1/7

compared with high carb/low saturated fat diets, low carb/high saturated fat diets are BETTER at improving triglyceride levels, HDL-C, fasting and postprandial blood glucose levels, and insulin concentrations
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http://www.nutritionandmetabolism.com/content/2/1/35

The effects of a low-carbohydrate, ketogenic diet on the polycystic ovary syndrome: A pilot study. It "led to significant improvement in weight, percent free testosterone, LH/FSH ratio, and fasting insulin in women with obesity and PCOS over a 24 week period."
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http://www.nutritionandmetabolism.com/content/2/1/28

A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease

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http://www.nutritionandmetabolism.com/content/2/1/21

The case for NOT restricting saturated fats on a low carb diet.
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http://www.nutritionandmetabolism.com/content/2/1/16

A case for low carb diets in diabetes management
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http://www.nutritionandmetabolism.com/content/2/1/5

fructose causes insulin resistance and metabolic syndrome (review paper)
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http://www.nutritionandmetabolism.com/content/1/1/14

Review on "Atkins Diabetes Revolution: The Groundbreaking Approach to Preventing and Controlling Type 2 Diabetes" by Mary C. Vernon and Jacqueline A. Eberstein

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http://www.nutritionandmetabolism.com/content/1/1/13

in low carb vs. low fat diet, only the low carb diet shows a preferential loss in the truncal region!
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http://www.nutritionandmetabolism.com/content/1/1/7

Metabolic aspects of low carbohydrate diets and exercise
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http://www.nutritionandmetabolism.com/content/1/1/6

Metabolic response of people with type 2 diabetes to a high protein diet

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other relevant open access articles:

http://www.nutritionandmetabolism.com/content/6/1/23

compared several diet types, and effects of exercise. showed "Greater improvements in waist circumference and body composition occurred when carbohydrate is replaced in the diet with protein" and fat loss was "significantly greatest" in the very low carb-high protein diet.
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http://www.nutritionandmetabolism.com/content/6/1/12

showed:
• Protein is a critical part of the adult diet

• Protein needs are proportional to body weight; NOT energy intake

• Adult protein utilization is a function of intake at individual meals

• Most adults benefit from protein intakes above the minimum RDA

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http://www.nutritionj.com/content/7/1/30

Spanish Ketogenic Mediterranean diet: a healthy cardiovascular diet for weight loss

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http://www.jmcreditorial.com/content/2/1/45

South Beach Diet associated ketoacidosis: a case report.

Hmmmm, happened w/ a diabetic patient. Concerning.
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http://www.nutritionandmetabolism.com/content/4/1/4

high saturated fat diet did not lead to fatty liver in rats
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http://www.nutritionj.com/content/5/1/26

Low carbohydrate diets in family practice: what can we learn from an internet-based support group.

Showed:
"The evidence from the survey suggests physicians who have been presented with patients desire to reduce carbohydrates are, in fact, open-minded on the subject. The negative connotations given by experts to the term "Atkins diet" may not be appropriate and the actual or perceived behavior of people who identify themselves as being on such a diet allow physicians to design a diet that is likely to be efficacious while not appearing iconoclastic. This last is probably the most important lesson that can be learned from the Active Low-Carber Forums."

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http://www.nutritionandmetabolism.com/content/3/1/23

A low-carbohydrate diet may prevent end-stage renal failure in type 2 diabetes. A case report

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http://www.biomedcentral.com/1472-6823/5/10

in a prior paper, the group showed:
"Our lab conducted a study on 24 domestic pigs in which a cereal-free hunter-gatherer diet promoted significantly higher insulin sensitivity, lower diastolic blood pressure and lower C-reactive protein as compared to a cereal-based swine feed."

In this paper, the group did a literature review and hypothesized that cereal-based diets cause increased disease in humans.
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http://www.jissn.com/content/1/2/21

Is a Calorie Really a Calorie? Metabolic Advantage of Low-Carbohydrate Diets

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http://www.jissn.com/content/1/2/7

Metabolic Effects of the Very-Low-Carbohydrate Diets: Misunderstood "Villains" of Human Metabolism

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http://www.nutritionandmetabolism.com/content/1/1/15

Thermodynamics of weight loss diets

Also asks "is a calorie a calorie?" in low carb diets.

and:
http://www.nutritionj.com/content/3/1/9 (opposing argument)
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http://www.nutritionandmetabolism.com/content/1/1/12

About metabolic syndrome resulting from abdominal obesity (and adipose tissue as an endocrine organ). Also states "The increase in leptin concentration after meals is not simply a result of a caloric load, but is in response to a signal that is not present following a fat load without carbohydrate [157]."
and "In their review, Westman et al cite many studies that have consistently shown that low-carbohydrate/high-fat diets consumed for more than seven days induce powerful metabolic adaptations to enhance fat oxidation [37]" and "In an elegant study, Bisschop et al support this by showing that high-fat, low-carbohydrate diets do not affect the action of insulin on total glucose disposal but decrease basal endogenous glucose production and improve insulin-stimulated nonoxidative glucose disposal [234]. Sharman et al demonstrated short term improvements of a ketogenic diet on lipids in normal weight men. These benefits occurred without total weight loss but there was evidence of a change in body composition toward more lean body mass [235]" and "Compared with patients with the lowest carbohydrate intake [246], a high-carbohydrate diet was associated with an odds ratio of 7.0 for liver inflammation. A high fat diet appeared to be protective, with those in the highest fat intake group having an OR of 0.17 [250]."
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http://www.nutritionj.com/content/3/1/19

Discusses carbs and cancers. States:
"Case-control studies and prospective population studies have tested the hypothesis that there is an association between a diet with a high glycemic load and cancer. The case control studies have found consistent increased risk of a high glycemic load with gastric [12], upper aero digestive tract [13], endometrial [14], ovarian [15], colon or colorectal cancers [16,17]. The prospective studies' results have been mixed. Some studies showed increased risk of cancer in the whole cohort with high glycemic load [18-20]; some studies found only increased risk among subgroups such as sedentary, overweight subjects [21-24]; other studies concluded that there was no increased risk for any of their cohort [25-28]. Even though there were no associations between glycemic load and colorectal, breast, or pancreatic cancer in the Nurses' Health Study there was still a strong link between diabetes and colorectal cancer [29].'' and of course diabetes is linked to many cancers.
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gosh! Thanks for posting all these links. Goodness knows when I'd find the time to look at all these things, but it's good to know they are here if I find some time.

amanda

Great list of research! And many thanks to Dr.'s Richard D. Feinman, Jeff S. Volek, Stephen D. Phinney, Cassandra E. Forsythe, Richard J. Wood, Maria Luz Fernandez, Eric C Westman, William S Yancy Jr., John C Mavropoulos, Mary Vernon, RK Bernstein and so many more for dieicating their lives to making this life altering research available for us.
Based on this research, you can understand how frustrating it is for these scientists when they can't get funding for larger long term studies.
Please help by signing my petition to the NIH to acknowledge existing science.
Your help is very much appreciated!
Here's the link:
http://www.thepetitionsite.com/1/ge...xperts-who-have