I really dislike Dr Mercola's style of taking self-diagnosis and anecdotes and trying to scare people with them. He uses the long chemical nomenclature of sucralose as a reason to fear it. A high school chemistry student would understand that that's just a scare tactic: would you panic if you found out that you ingested 2-methyl-3-hydroxy-4,5-bis(hydroxy-methyl)pyridine? Don't - because that's just vitamin B6. I find it hard to take people seriously when they write like that.

Any artificial substance carries with it some risk that you might react to it unfavorably - heck, even natural products carry that risk. Most of us know someone who could die from eating peanuts. I'm no Splenda apologist, but if you were to eat Dr Mercola's way, you'd practically have to grow your own vegetables, shoot your own animals, and never eat anything else. I'll take my chances with Splenda over sugar and almost-certain diabetes.