I wish there was more study on this subject. I look at the different responses...i.e. Adkpam loosing weight only through carb restrictions and Brobin only through calorie restrictions and excercise. Makes me wonder if degree of insulin resistance could be the culprit. In other words, if you are very resistant, you will respond best to carb restrictions, and if your insulin resistance is less, you respond less well to lowcarb.