I have never heard the term hyper-insulin-emic... the nurse may have dreamed that one up, lol. I was reading that the doctors are yet unsure if insulin resistance is a side effect of PCOS or a possible cause of it? I am insulin resistant too and tried Avandia for several months, but was not pleased with no wt loss, so I am new on glucophage as of 5 days ago. I know that you need to be on the low carb diet and on an oral hypoglycemic to prevent high blood sugars which can lead to permanant damage to alot of your body systems. Good luck to you and I agree, if you do not get good answers from your MD and nurses, go to another. And if they start speaking medical mumbo-jumbo that you do not quite understand or have never heard of, ask right away, what is that or could you explain that in English? Lol, that is what I do, and I am a nurse. None of them know everything. Have a great night.