Does anyone know about the success rate of avandia vs glucophage to assist with PCOS symptoms and wt loss? I know someone who gained wt on avandia, but I do not know if that is all related to the avandia. I could ask my doctor to try me on glucophage, but I would like to see some info from you all before I ask. The reason he put me on the avandia is pretty bad insulin resistance, and he said the glucophage has a lot of GI system side effects. Thanks for your help,