Thread: Incretin effect
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Old Sun, Jul-21-24, 12:29
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JEY100 JEY100 is online now
Posts: 13,748
 
Plan: P:E/DDF
Stats: 225/150/169 Female 5' 9"
BF:45%/28%/25%
Progress: 134%
Location: NC
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Dr Eades take home message to avoid highly processed foods and the combo of fat and carbs is the same as Dr Naiman, Marty Kendall's Optimising Nutrition, and the less well known, Cian Foley "Don't Eat for Winter" (in autumn, acorns and other nuts have that fat/carb combo). https://optimisingnutrition.com/esc...nfinite-autumn/

For me, a Ketogenic Diet was not the solution, the fat supplies too much energy for a less active older woman, and VLC reduces micronutrients and fiber. But if you are trying to gain weight, or have a goal of managing your natural insulin, different diet %s may work. Marty Kendall is managing the CGM's and insulin pump for two family members with T1 Diabetes, so he has more insight. Are you trying to gain muscle now?

I don’t know much about the incretin homones, but believe I am producing GLP-1 naturally through my food choices. This article is over year old but still relevant. How to Increase GLP-1 Naturally: Top Foods and Tips
https://optimisingnutrition.com/inc...lp-1-naturally/
Quote:
How Do Injectable Weight Loss Drugs Work?
Semaglutide, the primary ingredient in many weight loss drugs, mimics the natural GLP-1 hormone, promoting satiety and aiding in blood glucose regulation.

Your gut and brainstem naturally produce the signalling hormone GLP-1 after you consume food. GLP-1 signals satiety and lowers your hunger after eating.

GLP-1 is also an incretin hormone, enhancing insulin and suppressing glucagon secretion in the pancreas, thus lowering blood glucose.

An agonist is “a drug that binds to a receptor inside a cell or on its surface and causes the same action as the substance that normally binds to the receptor”. So, the GLP-1 receptor agonist works because the drug binds to a receptor and acts like your endogenously produced GLP-1.


Protein percentage is the most important food to Maximize my Satiety. But Vitamins, Minerals, and essential fatty acids also support GLP-1 that lowers hunger and has allowed weight loss/maintenance to be easier than it was on very low carb/keto. I follow a Nutrient Dense food list, not a particular level or % of fat and carbs. Nutrient Dense Foods for a Balanced, Healthy Diet
https://optimisingnutrition.com/nutrient-dense-foods-2/

Even better, consider foods from a Satiety Per Calorie approach.
The Most Satiating Foods: Eat Less and Feel Fuller
https://optimisingnutrition.com/most-satiating-foods/
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