I took Meridia for awhile. I don't think it is really a good idea to take it while doing this diet, for a few reasons. As GramnGramp said, you become immune to it very quickly, and you must keep upping the dosage to work. And secondly, it is about $125-$150 for 30 pills. Ridiculous!! It totally curbs your appetite - but i don't know why you would want to do that on this diet, where it is a matter of getting enough calories to keep your body healthy. IMHO, Meridia and other diet drugs and more for doing a low fat 'deprevation' diet plans.