Tue, Sep-22-15, 11:12
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Senior Member
Posts: 15,075
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Plan: mostly milkfat
Stats: 190/152.4/154
BF:
Progress: 104%
Location: Ontario
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821009/
This is a paper on ketone esters by Veech, and yeah, there is some prejudice against a ketogenic diet there;
Quote:
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There are important differences between feeding ketone esters (as in the study described earlier) and feeding a ketogenic diet. Ketogenic diets have been fed to humans since they were proposed by Russell Wilder at the Mayo Clinic in 19219 following the finding by Hugh Conkin10 that fasting resulted in a cessation of seizures in a child with intractable epilepsy. Since that time, the ketogenic diet has been used to treat drug-resistant epilepsy.11 Because of their rapid absorption, blood ketone levels of any desired level can be achieved by feeding the ketone ester, whereas feeding a ketogenic diet may produce diverse levels of ketone bodies depending upon the amount of carbohydrate or protein of the diet. A high-fat diet can lead to significant elevation of blood ketones, but also to an elevation of blood free fatty acids which in humans leads to a deterioration in both physical and cognitive performance.12 In addition, feeding a ketogenic diet can lead to an elevation of blood cholesterol and triglycerides which is undesirable in anyone over 17 years of age because of it atherogenic potential.13
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It would be interesting to see, in people who do get elevated cholesterol and triglycerides on a ketogenic diet (I think the second is rarer than the first), what happens with ketone esters being added in.
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