Fri, Apr-01-11, 20:42
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Senior Member
Posts: 5,065
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Plan: ZULCA!
Stats: 353/279.2/175
BF: For now...
Progress: 41%
Location: U.S.
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I knew I'd read something on his blog about his opinion--it's in the comments at this link:
http://www.proteinpower.com/drmike/...olic-advantage/
Quote:
Hi Dr. Mike—I respectfully express confusion:
Futile cycling vs. “acylation stimulating protein”.
I first read about ASP at Peter’s (Hyperlipid) blog. The pertinent link to his post is here: http://high-fat-nutrition.blogspot....n-its-hard.html.
Does one or the other control under certain conditions, or is more/less active? From this link (http://adipocyte.co.uk/ASP.htm) I think I get that ASP and insulin work together, both act on glucose, ASP is high in obese people but goes down when they’ve fasted for 4 weeks. All this, along with insulin increasing ASP 3-fold, makes me think of the carbs-insulin-obesity thing.
But then there’s this (also from that 2nd link, under “Regulators of ASP”): “postprandial rise in chylomicrons results in the strongest stimulus for ASP production (150 fold rise) in a dose dependent manner.”
And what about this: “Exercise increases ASP acutely by up to 67% in athletes with relatively rapid return to normal levels afterwards.” Now I feel like the world just turned upside-down. Exercise increases ASP which stores body fat so…does exercise cause us to store body fat? ...
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His answer:
Quote:
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The research group that found ASP is uncertain as to exactly what it does – if anything – in humans. The other group doing work on ASP has conflicting ideas as compared to the first group. Until it is all sorted out – if it ever is – I don’t put a lot of stock in ASP.
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