I get really bad arthritis if I eat wheat or refined sugar. It's not in my head, and as big as I still am, I should get the clicking (so loud that others can hear it) and pain in my knees whether I am eating these things (at least according to common knowledge about what causes joint problems). For a long time I thought it was starchy food in general, but I've found that it really only comes back if I eat a lot of food with wheat or refined sugar. I can eat a fair amount of carby fruit and even potatoes or rice and not have it. This isn't something that is new with low carb; I just always thought it had to do with my weight.

I also think people who have a lot of lower GI problems from carbs probably have yeast issues. I don't think it's a simple as stop eating carbs and all your health problems will go away. I think some carbs are more tolerated than others by people in general whether they have similar levels of carbohydrate.

We've sort of lived a long time without wheat and even longer without refined sugar. We may be designed with the ability to process carbs, even if it was just for times when the carbier fruits and plants were in season, but I think things like sugar, wheat, fruit juices, and HFCS are something totally different.