That's some good information cs_carver. I guess one always needs to remember that just because something is more natural rather than a competing refined extract of pharmaceutical quaility doesn't necessarily always make it harmless or even better than a pharmaceutical drug. I would still consider it a worthy competitor to some of the synthetic drugs put out by big pharma though...haven't really done much research on antidepressents myself yet. Maybe I will now just to have the knowledge in reserve.