Hi again,

You have all given me such hope today. I was wondering how long it takes to begin working. I exercise regularly (have for 5 yrs) but still not able to lose. I couldn't stay on any program due to severe insulin resistance. My daughter has PCOS but I didin't have any trouble conceiving. I'm very hopeful that metformin will work. I'm only on 500 mg, which sounds like it may not be enough. Should I ask my Dr. about increasing to 1000 mg?

Thanks again and bless all of you! This is an insidious and tormenting disorder. I have been struggling with this all my life and have just now come to understand what was wrong with me. I have never been able to metabolize carbs properly. Thank the Lord for all of these researchers, the internet and all of you!

Blessings always,
Grandma (in May)

P.S. This is the daughter that has PCOS, so I'm very thankful that she was able to conceive. She had fertility treatments to do so. She couldn't take Matformin but I'm going to tell her about the slow release type that I'm on.