The book Protein Power says that when we fall asleep, about 40 minutes later our bodies start releasing Human Growth Hormone. This is a VERY important hormone. It is the thing that allows most teenagers to scrarf down everything in site, be real couch potatoes and not gain a pound.

We older people still have HGH, but we can't access it very well. One way of accessing it better is to workout (weight train). Another is by sleeping. However if we EAT LATE, we can interfere with the release of HGH in our sleep. Particularly if we eat carbs before bedtime.

So I would say that yes, it will interfere with your weight loss and muscle building efforts to eat too late and then go to bed with the food still undigested.