Hi Rachel,

Um, first, the article refers to PERImenopause, not PRE-menopause. The difference between the two is about a decade, you still being a sweet young thing like me tee hee.

Most of the studies I've seen regarding soy isoflavones focus on one in particular - *genestein*, which exhibits some estrogen-like effects, including enhancing calcium absorption in bones. As long as we're still menstruating and producing our own natural estrogen, I see no need to take a supplement, but just my opinion of course. Besides enhancing calcium absorption, genestein-containing supplements are promoted for relieving other symptoms of menopause, such as hot flashes and night sweats.

A caution about genestein and the other soy isoflavones is that the estrogen-like effects CAN stimulate cancer cells that are particularly sensitive to estrogen - breast and ovarian (and prostate cancer in men too). In fact, the Breast Cancer Awareness group is cautioning patients to avoid soy in any shape or form. You should discuss this with your health care provider, if it's a concern for you.

I enjoy soy foods, and eat them often enough, but I don't go overboard. All things in moderation, eh?? My take is to get the nutrients from the whole food as much as possible.

Other things to do to prevent osteoporosis:

1.) calcium - from supplements, dairy foods, canned fish bones, almonds & sesame seeds, broccoli and cabbage

2.) vitamin D - produced in our bodies from sunlight. Note, the minimum exposure is one hour daily. Fine in summer, not fine in winter. I take cod liver oil capsules over the winter months just to be sure. The only other food source is fortified milk, which is high carbs. note - no other dairy product has added vit.D, only milk.

3.) weight-bearing exercise - studies show an increase of 10% in hip-bone density in post-menopausal women who participated in exercise involving gravity, such as walking, jogging, aerobic step, rebounding (mini-trampoline), etc. Note, swimming, lifting weights, stationary "machines" etc did not yield the same positive effect on bones, although they are certainly excellent exercises for other reasons - heart, strength, etc.

My suggestion, for what it's worth - save yer money!! Eat and enjoy soy foods like tofu and shakes, get plenty of calcium and vitamin D, and keep up with your exercise regimen. When the time comes, you can discuss soy isoflavone vs. hormone replacement therapy with your doctor.

from Doreen