Hi there. Yes, I too, along with many others I've found have been gaining weight on SSRI's (Zoloft, paxil, Prozac,etc.) I've been on Zoloft for 2 years and gained 25 lbs. I've managed to maintain and gain anymore, but I'm also on the lowest dose and eat a low carb, low cal diet and exercise everyday too. But, still can not loose this weight. I'm going to wean off this and try a natural alternative, called SAM-e.