I have been on synthroid or levoxyl for about 15 years now.....weight did not start coming off until I started LCing....ALSO many people who are hypothyroid also have elevated insulin levils.......ask for a fsting INSULIN test, not just a glucose test.....if it is off you can take glucophage and it helps with weight loss and sugar spikes and drops......combined with lc I feel fantastic! took many years of frustration to find this out.......if you have PCOS have your insulin checked as well.....my doc told me all theses things are connected......I had a horrible time getting pregnant, my doc ids now using glucophage with women who have PCOS and throid probs with great success.............just my observation