My daughter was just diagnosed with PCOS (and insulin resistance). She was put on low doses of glucophage, which is suppose to really help. It is used in higher doses for diabetes, but in low doses will control all the extra insulin her body is making. She acrtually lost 10 pounds eating everything over Christmas in about 3 weeks. We are going to go on the Insulin Resistance Diet together and are starting back to the gym, UG!!! Everything I read says diet and exercise are the biggest things you can do for PCOS. I look forward to sharing info. Blessings, Pam.