Hi, Joyce, I am taking both an anti-depressent and a high blood pressure medication. I do not have high blood pressure; I have tachyrhythmia, which means my heart beats too fast and out of rhythm. I have been on several different meds for this heart problem over a ten year period. In February 2004, my Dr. switched me to a new med. and I started Atkins in late April. My heart rate dropped from an average 83-88 bpm to 73-77bpm! In ten years I had never seen my heart rate so low. As I said, I do not have high blood pressure, but wanted to let you know of my positive experience with my own health problems through Atkins. Good luck, Carlene