You'd have to have an experiement where 4 groups of people ate different things. One group fat, one group protein, one group carbs and the last (control) just water. The food would all have to be unprocessed and have no additives. Even then it would be difficult because let's say you pick olive oil as your fat. Would the effect be the same with butter, or a poly-insaturated oil. If you pick egg whites as your protein, you can't eliminate compounds natural to egg whites. And so forth and so on

The best compromise would be to have, beside a control, a high fat low-carb meal (eggs, meat (not bacon, it's too processed), a high carb, "classical" breakfast (cereal, low-fat milk and a banana) and maybe throw in a mixed McD meal. The results of that would be much more interesting.