They've affected me much the same way that they affect the others that have posted on this thread. They stall me and they kill my digestive system. They don't affect my blood sugars though, which is curious. (I've tested on my wife's gestational diabetes testing supplies before and it didn't cause the glucose level to rise).

I ate the SA-filled candy during a stretch from October to late January/early-February. They caused a big time stall. I went on a clean induction, then introduced oil of oregano and acidophilus to my supplement regimen, and I've lost 17 lbs. since late February. I still drink Diet Rite, but I stay away from aspertame and caffeine.