Julie,
I take it(500mg) while I am pmsing and during any stressful situation from taking tests to being rushed or unhappy. I take it with all my supplements. However you shouldn't mix with other sedative type drugs such as alcohol, sleeping pills, anti-anxiety medication. I usually take it first thing in the morning and will take a benadryl in the evening to sleep. You can take two doses per day, it has always worked so well that I haven't needed the 2nd dose. You can take it everyday but I try not to take things I don't need. I buy it at the healthfood store. They can tell you if it will interact with medications you take.