My dad was a good 500 pounds. He died when he was only 45. I have always had a tendancy to be heavy but was always resolved to never get to 500 pounds. When I turned 45 I was a bit scared I didn't know if I would live through that year. But I did! I'm alive and I'm not sickly! Now I am losing weight. I had lost weight before and got down to 120 pounds so that does prove that I can do it no matter what my genes say. I would say that you can too!