I have been on Synthroid for many years now. My dose is ALWAYS changing. My TSH never seems to stay in one place. It has sure been a roller coaster ride, with emotions, weight and sleep problems. I just keep on pluggin away and trying everything I can to control my situation. I hope that the Atkins program will allow me more control of my weight, but it has been a pretty doggone slow process. I just keep trying and keep my chin up. Best of luck to ya.