What I mean by that, for you physiology experts, is....

Are there certain types of carbs, or combinations of carbs/fats/proteins, that will not have as potent a negative effect on us? Is it better to eat carbs quickly in one major binge, or is it better to spread them out? Is it better to eat them alone, or with proteins, or with fats? And if so, what ratio is ideal.

For example, If you have already made the decision to indulge (for this post, the reason does not matter, this is a physiology question) in bread, is it better to have a half a loaf in one sitting, or is it better to have 2 or 3 slices with breakfast, then lunch, then dinner? Better to have one big carb blowout event, or a few smaller ones in one day, with the same total carbs?....Carbs seem to go with fat naturally (bread & butter, pizza, ice cream etc.); is there any physiological benefit to add protein to the mix? For example, bread and butter is carbs and fat, no protein, but a meat sandwich is carbs and protein and fat; does the protein component affect how the body reacts?

Thanks.