Sat, Sep-06-03, 04:30
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Forum Founder
Posts: 37,415
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Plan: LC, GF
Stats: 241/190/140
BF:
Progress: 50%
Location: Eastern ON, Canada
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Holy Moly, talk about a trip down memory lane The forum was barely 9 weeks old
One thing to note, in the last article I'd posted .. it stated ... too much glutamine may be counterproductive. In humans, more than two grams is likely to result in less growth hormone production, less bicarbonate buffer, and probably no further energy benefit. In fact, elevated doses may overstimulate brain neurotransmitters and be dangerous.
Many current resources state that l-glutamine is safe at dose up to 20 and even 40g per day. However, there are still precautioins, for instance, those who are hypersensitive to monosodium glutamate (MSG) should use glutamine with caution, as the body metabolizes glutamine into glutamate. Also, because many anti-epilepsy drugs work by blocking glutamate stimulation in the brain, high dosages of glutamine may overwhelm these drugs and pose a risk to people with epilepsy.
Finally, in one case report high doses of the supplement L-glutamine (more than 2 g per day) may have triggered episodes of mania in two people not previously known to have bipolar disorder.
Doreen
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