Your body cannot distinguish between refined sugars and sugar in fruit. Even if the fruit has fructose, it still will get converted to glucose. All of the foods with sugar, be it natural or otherwise, will affect your blood sugar. And it's the blood sugar that affects your insulin that affects your hormones.

So yes, fruit will definitely cause hormonal problems with women who are already insulin resistant. It's best to eat fruit with a source of protein to help temper the insulin spike and to limit fruit to only a couple of servings a day, each one with a few hours between them.