The Great Vitamin D Experiment; Ongoing II
Here we go again!!!
Continued from: http://forum.lowcarber.org/showthread.php?t=332508 Quote:
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Posting these links to some great Vitamin D info here on the front page for future reference:
Vitamin D Council: http://www.vitamindcouncil.com/index.html The Vitamin D Council videos on YouTube: http://www.youtube.com/vitamindcouncil Vitamin D Action, GrassrootsHealth: http://www.grassrootshealth.net/ The UV Advantage – Dr Holick: http://www.uvadvantage.org/ A CONVERSATION WITH: MICHAEL HOLICK; Shining a Light on the Health Benefits of Vitamin D: http://www.nytimes.com/2003/01/28/h...html?sec=health Health Research Forum: http://www.healthresearchforum.org.uk/index.html SUNARC Sunlight, Nutrition and Health Research Center: http://www.sunarc.org/ Vitamin D: Is the Need and Evidence for Supplementation Being Ignored?: http://www.yourhealthbase.com/D_vitamin.htm The Antibiotic Vitamin: http://findarticles.com/p/articles/...0/ai_n16865477/ http://forum.lowcarber.org/showpost...1&postcount=763 The vitamin D miracle: Is it for real? http://www.theglobeandmail.com/serv...=all&print=true An Oldie Vies for Nutrient of the Decade http://www.nytimes.com/2008/02/19/h...ion&oref=slogin What’s the Real Story on Vitamin D? http://www.cbn.com/CBNnews/269033.aspx Heal Yourself with Sunlight http://www.newstarget.com/022315.html Vitamin D – The Miracle Cure? http://www.telegraph.co.uk/health/m.../14/hsun114.xml The virtues of Vitamin D: It's time we saw the light http://news.independent.co.uk/health/article2974479.ece The sunshine superstar: study reveals Vitamin D as 'wonder vitamin' http://news.independent.co.uk/health/article2447662.ece Bottled sunshine: The value of vitamin D http://news.independent.co.uk/health/article1525348.ece Vitamin D – The Sunshine cure http://news.independent.co.uk/health/article1220947.ece We all need a little dose of sunshine http://www.timesonline.co.uk/tol/li...icle3149273.ece Vitamin D: It's Not Just Another Vitamin : http://wholehealthsource.blogspot.c...er-vitamin.html “How much vitamin D should I take?”: http://heartscanblog.blogspot.com/2...uld-i-take.html Get some sun (or die): http://www.drbriffa.com/blog/2008/0...ome-sun-or-die/ Dr Briffa's Sunlight Archives: http://www.drbriffa.com/blog/category/sunlight/ Books: The UV Advantage: The Medical Breakthrough that Shows How to Harness the Power of the Sun for Your Health – Dr Michael Holick Quote:
The Healing Sun: Sunlight and Health in the 21st Century – Richard Hobday Quote:
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From Dr Briffa's blog:
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Thanks for the info.
I will buy some as well as walking in the sun. Barb |
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I applaud the D council and scientists alike for the push to break down these walls of woefully inadequate intakes/exposures, but even their more liberal recommendations still don't seem to be hitting the mark for me. When combined with all the synergistic nutrients (A, E, K2, calcium, magnesium, minerals in general, iodine, etc.), one can avoid any concerns of toxicity even at remarkably higher doses and the results can be greatly amplified. Zuleikaa, I have a document where I collected many a posts that I found interesting from this thread to keep for my personal collection. One of them had a post from you that mentioned that there was evidence that it was being understood that the D wasn't being destroyed to the extent once believed when getting continual sun exposure, justifying the fact that we are designed for higher D production/intake than is commonly believed. Might you be able to cite more specific resources as to where you come to this conclusion and posted the following in a previous D experiment thread of the past (on 02/09/2006)? No worries if not, just interested in looking into that further. Quote:
Edited to include this that I found in one of the original threads: Quote:
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Vitamin D: Why You Need This Vitamin Now
By Julie Upton
From Health magazine You may already know that vitamin D can help build strong teeth and bones, but wait until you hear what else it can do for the rest of your body. D can keep you trim, boost your mood, ward off sniffles, drastically cut your risk of cancer, and more. “We could prevent 150,000 cases of cancer annually if we could just increase vitamin D to optimal levels,” says Cedric Garland, a doctor of public health, a leading vitamin D researcher, and a professor of family and preventive medicine at the University of California, San Diego. That’s great news, right? Yes, except for one huge problem: A startling report found that more than a third of all women fail to get enough D for healthy bones—and more than 75% of us lack the higher amounts needed for the vitamin to do its disease-fighting best. Downing a daily glass of milk is a smart way to get more D. But the most significant source is sunlight, and that’s where the trouble lies. Our bodies produce D with exposure to ultraviolet radiation, but as we’ve gotten smarter about dodging skin cancer—staying out of the sun and slathering ourselves with mega-SPF sunblock—our vitamin D levels have plummeted. Fortunately, there are smart and safe ways to boost your intake while you enjoy all the benefits that vitamin D can deliver. Lower your risk of cancer Vitamin D may substantially cut the risk of breast, colon, prostate, and ovarian cancers, according to a growing body of research. In fact, Dr. Garland found that women with D blood levels that were more than double the current national average of 25 nanograms per milliliter (ng/ml) had a 50% lower risk of breast cancer than those with the lowest blood levels. Scientists believe that D helps regulate genes in a way that protects healthy cells and stops the growth of cancerous ones. There are receptors for vitamin D in virtually all of the body’s cells, and to “feed” them you need an adequate blood level of the vitamin. That depends not only on how much time you spend outside and what you eat but also on where you live. People living at higher latitudes, for example, soak up fewer UVB rays from November through March, which means they’re more likely to have low blood levels of vitamin D and a higher risk of cancer. In fact, studies have shown twice as many colon cancer deaths and 50% more breast cancer deaths in the far North compared with the sunnier South, Dr. Garland says. So how much sun is enough (link) to lower the risk of cancer without upping your risk of skin damage? Fight off winter weight gain Cold weather may seem a long way off right now, but more indoor time and fewer hours of sunlight can lead to a decrease in D production for many women. Researchers think that may explain why some women bulk up a bit when the temps fall: Low levels of D can cause a dip in leptin, a hormone that regulates appetite. When this happens, your brain may not send the signal that you’re full and should stop eating. Overweight women are especially at risk because excess fat can absorb vitamin D, making it unavailable to the body. Safeguard your healthy heart Vitamin D is thought to help lower blood pressure and regulate hormones that affect blood vessels and the muscles of the heart. Studies suggest that people with the highest D levels may have up to a 50% lower risk of heart disease. And researchers from Harvard Medical School reported a 62% increased risk of heart attacks or strokes among adults with the lowest blood levels of vitamin D, compared with those who have the highest levels of D. “We’ve also noticed that deaths from cardiovascular events are highest in the winter months, when vitamin D is generally at its lowest,” Dr. Garland says. Say good-bye to seasonal blues Low vitamin D levels may be linked to yet another winter bummer: seasonal affective disorder, a type of depression that is more common in northern states. Researchers believe that vitamin D helps keep the brain flush with the “happy hormone,” serotonin, which plays a critical role in regulating mood. The nutrient also seems to offer a lifetime of brain-health benefits, from aiding development in infants to keeping adults sharp in their later years. “Vitamin D receptors in the brain seem to turn on several genes that are important for normal neurological function,” says Bruce Hollis, PhD, a vitamin D researcher and professor of molecular biology at the Medical University of South Carolina. Boost your defenses against colds and flu Research shows that colds and the flu are worst when vitamin D levels decline, and they tend to hit hardest in countries at higher latitudes, where D levels tend to be lowest. So should we pitch out the C and hail the “sunshine vitamin” as the cure for the common cold? Experts aren’t making that claim just yet, but there’s compelling evidence that keeping your D level high may slash your chances of picking up the bug that’s going around the office. In one study, women who took 800 IU of vitamin D daily were three times less likely to develop colds or the flu—and those who popped 2,000 IU reported even fewer symptoms. Small wonder some scientists have started calling D the “antibiotic vitamin.” Prevent autoimmune disorders Vitamin D seems to interact in a protective way with genes that raise the risk for diseases like multiple sclerosis (MS), a debilitating nerve illness that strikes mostly young women. In one Harvard University study, researchers found a 40% lower risk of MS in women who took a daily supplement of at least 400 IU of vitamin D. In fact, some studies suggest that vitamin D may help prevent many other autoimmune disorders—including rheumatoid arthritis, type 1 diabetes, and Crohn’s disease. Even in healthy women, low levels of vitamin D may lead to increased inflammation, a negative response of the immune system. Build stronger bones The work that D does with calcium to keep bones healthy may be old news, but it’s no less important, especially for women. Osteoporosis and fractures due to bone weakness strike up to half of all females, according to the National Osteoporosis Foundation, and loading up on calcium-rich foods may not help much if you’re D-deficient. The nutrient helps your body absorb calcium and phosphorus, minerals that enhance bone strength. A supplement can help: A recent study found that, regardless of their calcium intake, women who added 482 to 770 IU of vitamn D slashed their risk of fractures by up to 20%. http://eating.health.com/2009/05/19/vitamin-d-you-need/ |
From Dr Briffa's blog:
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Jason I can't remember where I read that but it made a definite impact on me. I think it's why a level of <200 ng/ml. has become the safe standard. |
From The Times
London, UK 30 May, 2009 Quote:
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Thanks for your continued posting of articles & information as you stumble across them, Demi.
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I edited my previous post to include citation from a piece I stumbled across in the old thread that satisfied my appetite (for now). |
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And with that in mind, here's another article on Vitamin D in the British media this morning: Quote:
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Today's D thought (among many)
If one of the MP's arguments is correct, that exogenous 25(OH)D (from food and supplements) deactivates the VDR (which of course I disagree with due to scientific explanations I've come across to the contrary), then why is it that now that I'm taking mega-doses of exogenous D3 my skin is much more resilient against the exposure to UV rays from the sun? If the exogenous D were deactivating my VDRs, then I would logically expect to be seeing the opposite reaction given that there is evidence (presented previously) that D metabolites play a role in protecting the skin from UV radiation, resulting in less burning and damage and more tanning.
I just got inside from laying out in the noon-time sun and not even a trace of pink or redness. I'm tanning beautifully and can tolerate being outdoors much better now and my skin is looking and feeling its best now that I am feeling more 'D replete' (and also A replete, as it is essential for the full functioning of D). The cholecalciferol-phobia about going to high is rampant and unfortunate. It truly is all about balance. "Life in its fullest is Mother Nature obeyed." Quote:
Do you guys notice how I'm more upbeat and posting more frequently when I'm obtaining adequate, or optimal, fat soluble nutrients (especially D)? |
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Vitamin D, Proteinuria, Diabetic Nephropathy, and Progression of CKD.Agarwal R.
Indiana University School of Medicine and Richard L Roudebush VA Medical Center, Indianapolis, Indiana. Although the endocrine effects of vitamin D are widely recognized, somewhat less appreciated is that vitamin D may serve paracrine functions through local activation by 1-alpha-hydroxylase and thus maintain immunity, vascular function, cardiomyocyte health, and abrogate inflammation and insulin resistance. In the kidney, vitamin D may be important for maintaining podocyte health, preventing epithelial-to-mesenchymal transformation, and suppressing renin gene expression and inflammation. Replacement with pharmacologic dosages of vitamin D receptor agonists (VDRA) in animal models of kidney disease consistently show reduction in albuminuria, abrogation of glomerulosclerosis, glomerulomegaly, and glomerular inflammation, effects that may be independent of BP and parathyroid hormone, but the effects of VDRA in preventing tubulointerstitial fibrosis and preventing the progression of kidney failure in these animal models are less clear. Emerging evidence in patients with chronic kidney disease (CKD) show that vitamin D can reduce proteinuria or albuminuria even in the presence of angiotensin-converting enzyme inhibition. In addition to reducing proteinuria, VDRA may reduce insulin resistance, BP, and inflammation and preserve podocyte loss providing biologic plausibility to the notion that the use of VDRA may be associated with salubrious outcomes in patients with diabetic nephropathy. Patients with CKD have a very high prevalence of deficiency of 25-hydroxyvitamin D. Whether pharmacologic dosages of vitamin D instead of VDRA in patients with CKD can overcome the paracrine and endocrine functions of this vitamin remains unknown. To demonstrate the putative benefits of native vitamin D and VDRA among patients with CKD, randomized, controlled trials are needed. http://www.ncbi.nlm.nih.gov/pubmed/...Pubmed_RVDocSum |
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